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Additionally, certain medical interventions, particularly cancer immunotherapies using immune-checkpoint inhibitors (ICIs), have been reported to precipitate autoimmune thyroiditis by enhancing T-cellmediated immune responses and breaking self-tolerance (Barroso-Sousa et al

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10.1155/2011/796025 9 KlicekR.KolencD.SuranJ.DrmicD.BrcicL.AralicaG.et al (2013)

It is also possible that selenium may have beneficial effects in moderate-to-severe GO, especially when patients are selenium-deficient